KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2AK4
All Species:
17.88
Human Site:
Y1199
Identified Species:
39.33
UniProt:
Q9P2K8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2K8
NP_001013725.2
1649
186838
Y1199
Q
E
R
N
Y
S
I
Y
L
N
H
T
M
L
L
Chimpanzee
Pan troglodytes
XP_001140245
1649
186793
Y1199
Q
E
R
N
Y
S
I
Y
L
N
H
T
M
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535431
1633
184740
Y1201
Q
E
R
N
Y
S
I
Y
L
N
H
T
M
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ05
1648
186468
Y1198
Q
E
R
N
Y
S
I
Y
L
N
H
T
M
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518247
1608
180821
F1158
Q
E
R
N
Y
N
V
F
L
N
H
T
A
L
L
Chicken
Gallus gallus
XP_421203
1656
188583
Y1205
Q
E
R
N
Y
S
I
Y
L
N
H
T
S
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002667149
1483
168725
E1072
H
L
K
R
Y
S
I
E
R
V
F
R
P
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120977
1130
130476
F719
R
D
A
R
D
G
K
F
T
R
F
Q
I
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785160
1605
181469
R1191
L
K
R
Y
S
I
E
R
V
Y
R
E
R
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX30
1241
140303
F830
L
L
S
D
C
P
Q
F
S
R
K
T
V
K
L
Baker's Yeast
Sacchar. cerevisiae
P15442
1659
190175
I1178
E
K
T
N
T
F
F
I
L
N
H
A
D
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
89.7
N.A.
90.5
N.A.
N.A.
74.7
72.3
N.A.
52.6
N.A.
N.A.
27.9
N.A.
40.4
Protein Similarity:
100
99.9
N.A.
94.3
N.A.
94.9
N.A.
N.A.
84.4
84.5
N.A.
67.4
N.A.
N.A.
44
N.A.
59.4
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
73.3
93.3
N.A.
20
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
93.3
93.3
N.A.
26.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
26.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.7
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
10
55
0
0
0
0
10
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
28
0
0
19
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
55
10
0
0
0
0
10
10
0
% I
% Lys:
0
19
10
0
0
0
10
0
0
0
10
0
0
19
10
% K
% Leu:
19
19
0
0
0
0
0
0
64
0
0
0
0
55
82
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% M
% Asn:
0
0
0
64
0
10
0
0
0
64
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% P
% Gln:
55
0
0
0
0
0
10
0
0
0
0
10
0
10
0
% Q
% Arg:
10
0
64
19
0
0
0
10
10
19
10
10
10
10
0
% R
% Ser:
0
0
10
0
10
55
0
0
10
0
0
0
10
0
0
% S
% Thr:
0
0
10
0
10
0
0
0
10
0
0
64
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
10
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
64
0
0
46
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _